A battle 500 years in the making rages on as the effects of the mysterious drug Zone-00 takes hold of Tokyo's demon population.  Now it's up to Shima and Kujo to take matters into their own hands to restore order before it's too late.  Are they strong enough to prevail or will they need to enlist help from other creature kind as they close in on the mastermind behind the mysterious drug?

From the artist of Trinity Blood comes a dark, suspensful tale in which two centuries-old enemies fight together to save humanity!